mri images  (Kaggle Inc)

Journal: Ultrasound in Obstetrics & Gynecology

Article Title: Morphological patterns of fetal lateral ventricular border irregularities: descriptive study

doi: 10.1002/uog.70217

Figure Lengend Snippet: Nodular protrusion patterns of lateral ventricular border irregularities representing periventricular nodular heterotopia in three female fetuses with FLNA gene mutation, and corresponding schematic diagrams. (a,b) Case NP1 at 37 weeks: (a) axial transvaginal ultrasound shows multiple diffuse, bilateral, contiguous small nodular protrusions along the lateral ventricular border (LVB) (arrows) with intermediate echogenicity; and (b) corresponding T2‐weighted magnetic resonance imaging (MRI) shows low‐signal nodules isointense to cortex (arrows). (c,d) Case NP3 at 25 weeks: (c) sagittal transvaginal ultrasound shows small nodular protrusions along lower LVB (arrows) and undulating pattern along upper LVB (arrowheads); and (d) coronal transvaginal ultrasound demonstrates a squared anterior horn (arrowhead). (e,f) Case NP4: (e) sagittal transvaginal ultrasound at 26 weeks shows undulating LVB pattern (arrowheads); and (f) T2‐weighted MRI at 28 weeks demonstrates multiple small nodular protrusions along the upper LVB (arrows).

Article Snippet: We searched the electronic ultrasound and magnetic resonance imaging (MRI) databases of Wolfson Medical Center, Holon, Israel; Sheba Medical Center, Ramat Gan, Israel; and Bnai‐Zion Medical Center, Haifa, Israel, for examinations performed between 1 January 2014 and 31 December 2022 owing to suspected fetal anomalies or intrauterine infection.

Techniques: Mutagenesis, Magnetic Resonance Imaging

Journal: Ultrasound in Obstetrics & Gynecology

Article Title: Morphological patterns of fetal lateral ventricular border irregularities: descriptive study

doi: 10.1002/uog.70217

Figure Lengend Snippet: Nodular protrusion patterns of lateral ventricular border irregularities and corresponding schematic diagrams. (a–c) Case NP5, diagnosed prenatally with periventricular nodular heterotopia and hemorrhage‐related aqueductal stenosis leading to hydrocephalus. Sagittal (a) and coronal (b) transvaginal ultrasound at 33 weeks shows multiple small diffuse nodular protrusions (arrows). (c) Axial T2‐weighted magnetic resonance imaging (MRI) confirms nodular protrusions (arrows). Susceptibility artifact on heme‐sensitive MRI sequence (not shown) suggested early intraventricular hemorrhage as probable etiology for aqueductal stenosis. (d–f) Case NP12, diagnosed prenatally with tuberous sclerosis complex. (d) Sagittal transvaginal ultrasound at 32 weeks shows nodular protrusions with a large nodule at the caudothalamic groove (arrows). Cortical and subcortical echogenic foci consistent with tubers are also seen. Sagittal (e) and axial (f) T2‐weighted MRI shows hypointense subependymal nodules (arrows).

Article Snippet: We searched the electronic ultrasound and magnetic resonance imaging (MRI) databases of Wolfson Medical Center, Holon, Israel; Sheba Medical Center, Ramat Gan, Israel; and Bnai‐Zion Medical Center, Haifa, Israel, for examinations performed between 1 January 2014 and 31 December 2022 owing to suspected fetal anomalies or intrauterine infection.

Techniques: Magnetic Resonance Imaging, Sequencing

Journal: Ultrasound in Obstetrics & Gynecology

Article Title: Morphological patterns of fetal lateral ventricular border irregularities: descriptive study

doi: 10.1002/uog.70217

Figure Lengend Snippet: Patterns of lateral ventricular border irregularities (LVBI) observed with malformations of cortical development, and corresponding schematic diagrams. (a–c) Case M2, diagnosed prenatally with atretic posterior encephalocele. Sagittal (a,b) and coronal (c) transvaginal ultrasound at 24 weeks shows a mixed LVBI pattern including undulations (arrow heads), wedge‐shaped indentation (hollow arrow) and abnormal sulcation (curved line). Autopsy demonstrated periventricular nodular heterotopia (PNH) and subcortical heterotopia. (d,e) Case M1. (d) Sagittal transvaginal ultrasound at 24 weeks shows mixed LVBI pattern, including undulations (arrow heads) and wedge‐shaped indentation (hollow arrow). (e) Coronal transvaginal ultrasound at 24 weeks shows abnormal sulcation overlying ventricular border (curved line). Associated anomalies in this female fetus, including agenesis of the corpus callosum and retinal coloboma, suggest Aicardi syndrome. (f,g) Case M3. (f) Sagittal transvaginal ultrasound at 35 weeks shows diffuse mixed LVBI pattern with wedge‐shaped indentations (hollow arrows) and nodular protrusions (arrows). (g) Coronal T2‐weighted magnetic resonance imaging (MRI) at 35 weeks shows corresponding nodules isointense to cortex (arrows), consistent with PNH, and wedge‐shaped indentations (hollow arrow). Additional brain malformations and retinal coloboma in this female fetus support a diagnosis of Aicardi syndrome. (h–j) Case WI13. (h) Coronal transvaginal ultrasound at 32 weeks shows a deep wedge‐shaped indentation (hollow arrow), extending into unilateral cleft schizencephaly. (i,j) Coronal T2‐weighted MRI at 32 weeks (i) better delineates the transmantle cleft (hollow arrow), with a corresponding wedge‐shaped indentation in the sagittal view (j) (hollow arrow). Ipsilateral perisylvian polymicrogyria is evident (curved line).

Article Snippet: We searched the electronic ultrasound and magnetic resonance imaging (MRI) databases of Wolfson Medical Center, Holon, Israel; Sheba Medical Center, Ramat Gan, Israel; and Bnai‐Zion Medical Center, Haifa, Israel, for examinations performed between 1 January 2014 and 31 December 2022 owing to suspected fetal anomalies or intrauterine infection.

Techniques: Magnetic Resonance Imaging, Biomarker Discovery